Skin hyperpigmentation is a global concern; Here’s how to treat them and control their reappearance.


Dark spots affect all skin types, mostly women, and are a concern both for their aesthetic affectation and for their negative effect on the psycho-emotional level and on quality of life.

Dark spots affect all skin types, mostly women, and are a concern both for their aesthetic affectation and for their negative effect on the psycho-emotional level and on quality of life.

There are different types of dark spots differentiated by their origin and distribution on the skin, such as melasma, spots of inflammatory origin (HPI), solar lentigines, senile spots or freckles. They can appear due to numerous triggering factors, the most important being unprotected solar radiation, but also others such as genetic predisposition, inflammatory processes, hormonal changes, some photosensitising medications such as oral contraceptives or some anti-inflammatory drugs, antibiotics etc...

At mesoestetic® we are specialists in depigmentation. More than 30 years of research have allowed us to consolidate professional solutions of proven efficacy such as dermamelan® and cosmelan®, and home solutions such as melan tran3x concentrate and melan tran3x gel cream.

dermamelan® is the depigmentation treatment that treats dark spots and regulates the overproduction of melanin, inhibiting and controlling the reappearance of new blemishes in the long term.

It consists of a single session in a doctor's office and a cosmetic regimen to be carried out at home, defined by the medical professional, with results after 4 months of treatment.

cosmelan® is the world's leading professional depigmentation method, with 30 years on the market, which eliminates existing dark spots and prevents their reappearance for short and long term results.

It combines a single session with an aesthetic professional with a cosmetic treatment to be carried out at home. The treatment lasts approximately 6 months.

melan tran3x is a home depigmentation treatment made up of two synergistic products: melan tran3x concentrate and melan tran3x gel cream acid. It is ideal for boosting and maintaining the results obtained after dermamelan® and cosmelan® treatments.

Are you worried about dark spots? Discover our wide range of solutions and treatments against skin hyperpigmentation and consult your dermatologist to choose the most suitable one for you.