depigmenting professional treatment

the world’s leading professional depigmenting method

cosmelan® is a integral professional depigmentation method for your spots.

cosmelan® is a depigmenting method that removes spots fully and prevents their reappearance for a short-term outcome, while being able to maintain hyperpigmentations under control for a longlasting outcome.

The cosmelan® method consists of 4-phases which are necessary to achieve the target outcome. Intense depigmentation in cabin in phase 1 and treatment for home use in phases 2, 3 and 4.

The synergistic action of the method products ensures: higher depigmenting efficacy, greater comfort during treatment and lower risk of repigmentation.

This dual action makes it a unique and integral treatment, affording complete and effective results:

- corrective action: it removes the deposits of melanin, a pigment that gives colour to the spot in the outermost skin layers.

- regulating action: it acts directly in the melanocyte, a cell where melanin is produced, to control its production and keep hyperpigmentation under control

Over 1 million patients. A long track record guarantees the efficacy of cosmelan® method.

Thousands of professionals treat hyperpigmentations with cosmelan® method and recommend it to their patients.

Dual action with a unique efficacy. Integral treatment with short and longterm results to maintain hyperpigmentation under control.

Excellent clinical results. Efficacy studies support its success in all types of skin, hyperpigmentations and ethnicities.


The cosmelan method pack contains:

Product for professional office use, in phase 1:
• Oil removing solution. Oil removing solution
• cosmelan 1. Intensive depigmenting facial mask - Products for home use in phases 2, 3 and 4.

cosmelan home pack:
• cosmelan 2. Home depigmenting cream that intensifies the results of cosmelan 1, keeping melanin production under control and preventing the appearance of new spots.
• melan recovery. Soothing and restorative balm for sensitive, reddened skin. Helps soothe the skin and restore its balance and comfort during treatment with cosmelan.
• melan 130 pigment control. Sunscreen with colour for pigmentation control. Protects the skin from broad-spectrum solar radiation and helps control skin pigmentation.

Treatment results

Before Before
Reduction of hyperpigmentation and improvement of the texture and appearance of the skin. Melasma (phototype I-III)
Before Before
Reduction of hyperpigmentation and improvement of the texture and appearance of the skin. Senile lentigo (phototype I-III)

1. Intense depigmentation

In the salon with removal at home

8 to 12 hours

Following a deep cleansing with the oil-removing solution, cosmelan 1 has a powerful depigmenting effect due to its high concentration of active ingredients. The product should be applied by the professional, who will establish the application time in each case. After the recommended application time, the patient should remove the product at home, completing the first phase. 

Instructions for use: apply the 10 g of the cosmelan mask and allow it to act using your professional judgment for 8-12 hours according to the indications on the above technical table for the pack.

Removal of the mask at home: rinse carefully with plenty of lukewarm water, multiple times if necessary, avoiding direct contact with the eyes. In case of erythema, tightness or a sensation of dryness, we recommend applying a layer of melan recovery, allowing it to act for 10-15 minutes.

2. Continuous depigmentation

At home

Month 1

48 hours after removing the cosmelan 1 mask, it is necessary to continue with the daily depigmentation routine to supplement the corrective action of the method and to regulate overproduction of melanin inside the melanocyte.

Instructions for use: apply cosmelan 2 three times a day (morning, midday and night), followed by melan recovery and melan 130 after daytime applications.


In the case of extreme sensitivity during this phase, consider spacing out the applications of cosmelan 2, without abandoning the treatment altogether.

3. Control of hyperpigmentation

At home

Months 2 and 3

At this point, it is important to treat the root cause of the blemish by regulating overproduction of melanin through constant regulation of the melanocyte. This controls both intra- and intercellular melanin production and prevents repigmentation.


Instructions for use: apply cosmelan 2 morning and night, followed by melan recovery, and melan 130 during the day. In case of sun exposure, reapply UV protection at midday.

4. Controlling reappearance

At home

Month 4 to 7

The tendency to develop dark spots represents an ongoing risk. During the control phase, the treatment prevents the reappearance of the treated spots and the formation of new ones, for a longer-lasting result.


Once the method is complete, we strongly recommend continuous use of sun protection as a permanent cosmetic treatment.


Instructions for use: apply cosmelan 2 at night, followed by melan recovery. During the day, apply melan 130 and reapply in cases of direct sun exposure.

Additional Information

Skin type all.
Application area face.
Procedure spots and hyperpigmentation.

Treatment information

Cosmetically indicated for the attenuation or eradication of acquired skin pigmentation imperfections of melanic origin, located on the face, neck, neckline and hands. It also enhances skin brightness and tone and helps to improve skin beauty.