Depigmentation treatment for medical use: dermamelan®
Details of the dermamelan® treatment.
Disorders of melanin pigmentation
Pigmentation concerns are a growing, global issue; they affect more than 90% of adults over the age of 50. Regardless of skin color, they are a significant issue because of their unattractive appearance and negative psychological and emotional impact, affecting quality of life. Melanogenesis is influenced by both exogenous and endogenous factors that can lead to a localized overproduction of melanin. This excess of melanin translates into unsightly spots of pigmentation, which in the majority of cases are harmless. They are acquired skin spots, different from those with a genetic origin.
It is a professional treatment for topical bleaching that is versatile, easy to use and adapts to any skin phototype. Treatment results in the reduction and removal of acquired melanin skin spots, as well as increasing the skin’s radiance and giving it a more even tone. It acts on the melanosome, halting melanin production for a long period of time, during which the peeling of the stratum corneum and the action of macrophages remove the deposits of melanin.
- Reversible inhibition of tyrosinase activity
The process of tyrosinase inhibition is only activated when the treatment is applied. Once treatment has ended, the enzyme recovers its activity and begins to make new melanin, especially if there is solar stimulation. As a result of this mechanism, topical bleaching agents must be applied repeatedly to obtain results.
- inhibitory action without damaging the melanocyte
In no case does the inhibition of tyrosinase cause the disappearance of the melanocytes, it merely stops or slows the production of melanin, meaning there is no risk of white spots appearing. The action of dermamelan® causes an accompanying inhibition in other enzymes that participate in the process of producing eumelanin, including dopachrome tautomerase, among others.
Detail of the sessions
Treatment with dermamelan® consists of two phases which ensure a long lasting and efficient result, due to the effects of the professional treatment being prolonged by the care at home. By making the melanin blemishes disappear it achieves a lighter, more luminous skin.
Intensive salon treatment
The professional performs a study of the patient’s hyperpigmentation using a Wood’s lamp (blacklight). Once the type and severity of the spots has been identified the treatment is personalized, adjusting the products to be used and application times. With this level of personalization the best results are obtained according to the particularities of each patient.
The professional then prepares the skin by performing a peel with specific products depending on the case.
- Cases of mild hyperpigmentation: gentle exfoliation with dermamelan degreasing solution by mesoestetic® to facilitate the penetration of the active ingredients.
- Cases of severe hyperpigmentation: exfoliation with mesopeel mandelic 30% by mesoestetic®, ampoule of mandelic acid 30% that accelerates the natural flaking of corneocytes and therefore, the elimination of melanin.
Once the skin is prepared, usually 48 hours after the peel, the bleaching method is applied with dermamelan mask®, which contains high concentrations of active ingredients with bleaching action. When the mask has been applied the patient can return home, removing the mask later with soap and water once the time recommended by the professional has elapsed.
- Phototypes I y II: 8 hours
- Phototypes III and IV: 10 hours
- Phototypes V and VI: 12 hours
It is possible to use the mask two times after 15 days, in combination with the application at home of the maintenance cream, dermamelan treatment®.
Maintenance at home
1. Remove the mask
The patient goes home wearing the mask and leaves it to work between 8 and 12 hours, following the instructions of the professional. The product is easily removed with soap and water.
To improve the skin’s radiance and tone: It is recommended to use ampoules of Vitamin C 20% by mesoestetic® twice a week, on the face and neck, before application of the dermamelan treatment® mask. Opened ampoules can be stored in the refrigerator for up to 48 hours.
Cases of generalized hyperpigmentation: Apply the dermamelan treatment® maintenance cream following the method 3, 2, 1:
- 3 application during the first month: morning / midday /night
- 2 applications during the second and third months: morning / night
- 1 application from the fourth to the seventh month: night
Cases of localized hyperpigmentation: Twice a day apply melanogel touch by mesoestetic®, whose roll-on format permits its convenient application to localized blemishes, accelerating the process of their depigmentation.
Mesoestetic integral solutions